Floccinaucinihilipilification!

-Do you think I may be too quick to find fault with things and people?
-Yeh.
-Th' 'floccinaucinihilipilification' process.
-Th' what?
-Floccinaucinihilipilification!! It means 'the estimation of something as valueless'!
-You've been randomly reading th' dictionary, haven't you?
-Yes. That and my natural tendency toward antifloccinaucinihilipilification!!

From 'Zippy', published March 14, 1996